2022 Winter Conference on Plasma Spectroscopy
Glass Expansion Lunch and Learn ICP Workshop
Room: Coronado 1
Scheduled: Tuesday, January 18 - 11:45 AM - 3:45 PM
Join us on Tuesday, January 18 for an afternoon full of ICP information. Starting with sample prep, looking at a wide variety of ICP techniques for various sample types, and even addressing standards throughout the process, we've got all of your ICP questions covered. Register for Winter Plasma Conference at the discounted pre-December 17th rate (use code Lunch&Learn22) and attend the Glass Expansion Lunch & Learn for free. Please note: Registration for both events is required. Register for Winter Conference using the registration and hotel forms, register for the Lunch & Learn using the form on the right.
Come by at 11:45 AM to grab a lunch and settle in for an afternoon packed with tips and tricks from the experts!
12:00 PM: Intro/Host - Ryan Brennan – Glass Expansion
Vessel Cleaning Techniques to Achieve Lower Analytical Blanks.
Presenter: Bob Lockerman – CEM
Abstract: Sample preparation is a critical step in trace metals analysis and an area that can introduce contaminants, if steps are not taken to prevent them. Vessel cleaning is extremely important. How you clean your vessels is based upon your detection limits and at what level you are wanting to quantify (ppm, ppb, ppt). We will look at a variety of cleaning methods available to analysts in order to determine the best techniques for your laboratory.
Comparing spray chamber performance in a long-term stability study using the Advion Interchim Scientific Solation ICP-MS.
Presenter: Joseph Brady – Advion Interchim Scientific
Abstract: With the release of Advion Interchim Scientific’s new Solation ICP-MS, it was critical to select the most optimal sample introduction system to suit a variety of different industries. In this particular case study, the company compared the long-term stability performance of two popular quartz cyclonic spray chamber designs. A 400 µL/min MicroMist® glass concentric nebulizer was used in all experiments. The signal intensity and precision (%RSD) of a 1 ppb multi-element standard was monitored for over 14 hours. These results were used as the basis to select which cyclonic spray chamber model would be the standard option on Advion Interchim Scientific’s new Solation ICP-MS. This evaluation highlights the performance of the Solation ICP-MS and unique design advantages of the standard Twister® cyclonic spray chamber.
Making the switch from the Scott spray chamber to a Peltier cooled cyclonic on ICP-MS.
Presenter: Thomas Kozikowski – Inorganic Ventures
Abstract: Many new ICP instruments ship from the manufacturer with a Scott spray chamber installed and utilized for instrument setup. The Scott spray chamber dates to the early 1970s and is still widely used in the industry today, but the main design limitation with the Scott design is washout performance. Many laboratories are hesitant to make major changes to their ICP setups for a variety of reasons including cost, method validation, and even instrument hardware limitations. The focus of this presentation will be on the technical aspects of making the change from the Scott spray chamber on an Agilent 7900 ICP-MS that is equipped with the Ultra High Matrix Introduction (UHMI) option to a Peltier cooled cyclonic (PCC) spray chamber from Glass Expansion. Several matters will be discussed beginning with calibration standard recommendations and chemical compatibility issues that may be contributing to poor washout. Common and specialty rinse solutions will be compared and suggested for certain troublesome elements including B, Hg, Mo, Sb, Bi, Os, and more. Finally, the raw data comparing the washout performance of the Scott vs the Cyclonic will be presented while experimenting with different rinse solutions and other introduction system variables to mitigate issues with those troublesome elements.
The analysis of Li6 and Li7 isotopes in a Dimethyl Carbonate -DMC matrix (as used for Li battery manufacturing) by means of a modern ICP OES system featuring a Dual Side On Interface (DSOI).
Presenter: Dion Tsourides – Spectro
Abstract: The analysis of DMC, which is a starting raw material matrix for Li battery manufacturing, will be explored. The presentation will cover trace impurities, proper analytical calibration, sample introduction setup and the ability to separate the Li6 from Li7 isotopes using a new state of the art ICP OES system, which offers a more robust alternative to ICP MS (no digestion and the ability to run the DMC organic samples directly).
Single-cell inductively coupled plasma time-of-flight mass spectrometry (sc-ICP-TOFMS) applied to the study of algae cells.
Presenter: Yannick Bussweiler – TOFWERK
Abstract: Recently, growing interest in single-cell analysis has been observed in fields as diverse as ecotoxicology, metallomics, medical diagnosis and pharmaceutics. Single-cell analysis using ICP-MS (sc-ICP-MS) has greatly matured as a technique over the past few years, namely by benefiting from recent software and hardware developments for nanoparticle analysis. With high-speed acquisition and simultaneous analysis of all isotopes, the icpTOF is the ideal instrument for the analysis of transient multi-element signals, such as those produced by single particles and cells. Single-cell ICP-TOFMS enables cellular elemental fingerprinting and is a promising approach for multiplexed analysis of cells. However, despite all these technical improvements, a major challenge in single-cell analysis remains on the practical side and relates to the transport of intact cells into the plasma with high transport efficiency. This presentation will highlight one recent application example in which algae cells were exposed to cerium oxide nanoparticles and were measured using the combination of the icpTOF S2 from TOFWERK with the Single-Cell Sample Introduction System (SC-SIS) from Glass Expansion. The simultaneous detection of all elements using the icpTOF allows for the measurement of all relevant elements in one cell (e.g., Mg, P, Fe, and Ce) and provides a direct quantitative measure of the nanoparticle-cell association. Additional information regarding the sample preparation (e.g., the effectiveness of washing step) can also be derived from such multi-element data.
The Path to Formulating an Os Solution Standard that is Traceable to the International System of Units (SI).
Presenter: Madeline Gozzi – Inorganic Ventures
Abstract: The purpose of this work was to develop an accurate osmium (Os) solution standard that is traceable to the International System of Units, the SI. A gravimetric reduction (GR) method was developed to accurately assay the Os in ammonium hexachloroosmate salt, (NH4)2OsCl6, the chosen starting material for the Os solution standard. This gravimetric reduction method was also applied to -200 mesh high purity Os metal powder, which served as an independent source of Os for comparison. An alkali fusion method was developed to create water soluble salts from the Os metal gravimetric reduction products of both the (NH4)2OsCl6 and the -200 mesh high purity Os metal powder. Quantitatively prepared Os solutions from each of these water soluble salts were compared by inductively coupled plasma spectrometry, ICP-OES. The purities of the Os starting materials were determined by quantitatively performed trace metallic impurities analysis, by ICP-OES and ICP-MS; the O, N, and H impurities were determined by inert gas fusion analysis. The percent purities of the starting materials were applied as corrections to the Os assay results obtained by GR. The agreement between these Os solutions, corrected for random and systematic errors by error budget analysis, confirmed the accuracy of the Os assay in the (NH4)2OsCl6. The SI traceability of the Os assay in the (NH4)2OsCl6 salt was established through the gravimetric reduction procedure, and the purity analysis of this material. An SI traceable Os solution standard was gravimetrically prepared from this batch of (NH4)2OsCl6, based on the accurate Os assay and the percent purity of the starting material.
Laser Ablation ICP-MS: Not just rocks.
Presenter: Lucas Smith – Teledyne Photon Machines
Abstract: This workshop will provide a brief explanation of what Laser Ablation ICP-MS is all about, how it works and why we use it. We will then move on to provide examples of different, applications that demonstrate the incredible power and flexibility provided by the technique. Using a micron scale laser beam, we will show how we can generate either fully quantitative or qualitative data from nearly any solid material, both quickly and efficiently. We will look at data for isotope ratio geochronology; and the power of elemental imaging applications where we generate ‘heat maps’ showing how elemental concentrations vary across a sample at the micron scale. Laser ablation ICP-MS has historically been an important part of the geologist’s tool kit, but we hope to show you how recent developments in this technology allow us to generate some incredible data across an increasing number of application areas far beyond the scope of (just) rocks.
Analysis of Elemental Impurities in Lithium Hexafluorophosphate Electrolyte Solution for Lithium Ion Batteries by ICP-OES.
Presenter: Sabrina Antonio – Thermo Fisher Scientific
Abstract: Increased energy demand combined with the rising cost and environmental issues associated with the use of refined fossil fuels drive the demand for green energy technology generation, especially for the automotive industry. Lithium-ion batteries used in electric vehicles are an important part of the effort to transition from gasoline to greener energy generation.
The electrolyte within a lithium-ion battery is important for providing the necessary battery output and charging/discharging cycle performance. The most common inorganic salt in lithium-ion battery electrolytes is lithium hexafluorophosphate (LiPF6) as it exhibits the properties required for optimum battery performance. The presence of elemental impurities reduces electrolyte performance, hence testing of LiPF6 for a range of elements to ensure a product of high purity to use for lithium-ion batteries is needed. A fast and robust determination of elemental impurities in LiPF6 electrolyte solution using the Thermo Scientific iCAP PRO Series ICP-OES combined with an optimized sample introduction system, that includes the Glass Expansion ceramic torch, will be discussed in this presentation. Method development, detection limits, and demonstration of good sample measurement repeatability will also be discussed to demonstrate method performance.
Fast and Simultaneous Determination of Hydride and non-Hydride Forming Elements Using HydraMist Coupled to PerkinElmer High Throughput System (HTS) Using the Avio Series of ICP-OES.
Presenter: Chady Stephan – PerkinElmer
Abstract: Hydride Generation (HG) combined with Inductively Coupled Plasma - Optic Emission Spectroscopy (ICP-OES) is commonly used to improve the sensitivity of elements such as, As, Bi, Ge, Pb, Sn, Sb, Se and Te by 10 to 100 times, in applications requiring determination of trace and ultra-trace levels elements. However, in routine analysis, the determination of major elements as well as trace elements is often required, resulting in a switch between conventional pneumatic nebulization system and HG system. Making the analysis more complex, and increasing the analysis time.
By combining PerkinElmer’s High Throughput System with the HydraMist (Glass Expansion) we were able to measure both hydride generating and non-hydride generating elements simultaneously without any compromises in sample analysis time. In this work, food and Soil CRMs were analyzed with PerkinElmer Avio 560 ICP-OES. The hydride elements (As, Bi, Pb, Se, Sb) and non-hydride elements (Ca, Cd, Co, Cr, Cu, Fe, Ni, Mn, Ni, Zn) were measured in one sample run. All measured values were in great agreement with certified values. Excellent detection limits were achieved. The combination of HydraMist system and HTS provides superior performance in terms of analytical sensitivity, precision, and greater sample throughput.
Resolving Laboratory Challenges with Automated Sample Preparation.
Presenter: Jacob Herrington – Teledyne Cetac
Abstract: Sample preparation can be a time consuming, tedious and error prone endeavor at the best of times, but with current shortages in both staff and consumables it is becoming a bigger burden than ever before. The SimPrep Automated Liquid Handling Station was designed to remove the burden of sample preparation by providing a robust, reliable and easy to use platform that automates these tedious daily tasks. Better laboratory automation can help relieve the stress of staffing shortages and reduce the usage of difficult to obtain consumables.